Module 3 — Treatment Options for Kidney Failure
Sources: Condensed study notes based on Core Curriculum for the Dialysis Technician, 7th ed. (MEI), plus free CDC/CMS/NIDDK resources.
Treatment choice: the module’s frame
Study guide
- Kidney failure can be treated with a kidney transplant or dialysis; each can sustain life, sometimes for many years. The best option is the one that fits the person’s health, goals, schedule, support, and preferences.
- This chapter presents nine broad choices: transplant; two PD approaches; standard in-center HD; nocturnal in-center HD; standard home HD; daily home HD; nocturnal home HD; and active medical management without dialysis.
- The chapter’s central message is autonomy: patients may not realize they have choices or that they can change modalities. Staff should explain options without steering by convenience or fear.
Why answers are correct
- A technically effective treatment that prevents work, caregiving, sleep, travel, or preferred eating may be a poor life-fit. Matching treatment to what matters can improve engagement and quality of life.
- Fear and information gaps can make patients think they have no choice. Education, repetition, social-work support, and referral to the home-training nurse or doctor help patients decide.
Limitations / traps
- Do not promise that one modality is best for everyone or that a patient can automatically qualify for transplant or home therapy.
- The technician provides accurate, unbiased information within scope; do not diagnose, change a prescription, or answer an uncertain clinical question from memory. Ask the nurse.
Clinical pearl / safety
- Treat complaints about thirst, diet, fluid gain, long travel, work, childcare, or treatment symptoms as openings to identify a better-fit option—not as evidence of poor motivation.
Exam cue
- Good modality choice = clinical safety + patient goals + feasible support + informed preference.
Kidney transplant
Study guide
- A transplant places one healthy donor kidney in the recipient. The native kidneys generally remain in place; the graft is connected to the iliac vessels and ureter.
- Transplant is not a cure for kidney failure. A graft may never work or may last years to decades; rejection can occur whenever the immune system attacks it as foreign.
- The chapter reports better short-term graft survival for living-donor than deceased-donor kidneys (about 98% versus 94% functioning at one year; about 86.5% versus 76% at five years). These are chapter figures, not a guarantee for an individual.
- Recipients need lifelong immunosuppression while the graft functions. Possible effects include weight gain, stomach irritation, unwanted hair, dyslipidemia, hypertension, cataracts, bone/joint problems, infection, diabetes, and cancer.
- Transplant patients usually drink more water and have fewer diet limits than people on dialysis. If a graft fails, dialysis can resume and another transplant may be possible.
- Listing is not automatic. A transplant center evaluates physical and psychological readiness and applies its own rules. OPTN maintains the national deceased-donor list, but the supply is insufficient, so waits may be long.
- Donor sources:
- deceased donor;
- living blood relative;
- living unrelated donor.
- Potential living donors need health evaluation and blood/tissue compatibility testing. A kidney-paired exchange can match incompatible donor–recipient pairs with other pairs; an altruistic donor can start a longer chain.
- Kidney-pancreas (KP) transplant: selected people with diabetes and kidney failure may receive both organs. A simultaneous kidney-pancreas transplant can remove the need for dialysis and insulin while both grafts work. A pancreas graft may improve diabetic injury, but eligibility is program-specific.
- Preemptive transplant: transplantation before dialysis may be considered when GFR is about 20 or lower; a living donor is often needed because timing is predictable.
- Matching tools described by the chapter include KDPI, which estimates how long a donated kidney may last from donor characteristics, and EPTS, which estimates recipient post-transplant survival. ABO-incompatible transplant may be possible after immune desensitization.
Why answers are correct
- Transplant can restore more continuous kidney functions than intermittent dialysis, but it adds surgical risk, immune rejection risk, and medication toxicity. It is a treatment option, not a permanent cure.
- A donor match is not simply “same blood type”: programs weigh compatibility, expected graft longevity, recipient factors, and safety.
Limitations / traps
- Never imply that a person is “not trying” because they are not listed; age, comorbidity, psychological evaluation, donor supply, program criteria, and access all matter.
- Do not tell a patient to stop immunosuppressants or interpret possible rejection. New illness, infection, medication problems, reduced function, or concerning symptoms require the transplant team.
- Survival percentages are population estimates and may change with era, donor type, and patient selection.
Clinical pearl / safety
- A patient turned down by one program may be accepted by another because programs use different criteria. Refer questions to the transplant center and social worker rather than closing the door.
Exam cue
- Transplant = closest available approach to normal kidney function, but not a cure; lifelong immunosuppression and rejection surveillance remain.
Compare / contrast
| Feature | Transplant | Dialysis |
|---|---|---|
| Kidney work | One graft may provide continuous filtration and endocrine work | Replaces selected filtration/fluid removal intermittently or continuously by a modality |
| Main burden | Surgery, rejection, immunosuppressant effects, graft failure | Repeated treatment, access/catheter or PD infection risk, diet/fluid and schedule demands |
| Availability | Evaluation and donor/listing criteria; donor shortage | Several modalities, but access, training, resources, and medical suitability still matter |
| If treatment fails | Return to dialysis; sometimes re-transplant | Change modality, modify prescription, or consider transplant/medical management |
Dialysis as partial kidney replacement
Study guide
- During dialysis, a semipermeable membrane separates blood from dialysate. Water and selected wastes cross microscopic pores into dialysate; cleaned blood returns to the patient.
- Dialysis cannot reproduce all continuous kidney functions. A well-dialyzed person may still need medicines, anemia treatment, vitamin D, phosphate management, and careful fluid/electrolyte planning.
- Compared with healthy kidneys, dialysis generally removes only some water and wastes on treatment days, helps rather than fully controls electrolyte/acid–base balance and blood pressure, and does not make EPO or activate vitamin D. It can alter calcium and remove some phosphorus but less completely than healthy kidneys.
- Treatments should be comfortable and leave patients feeling well. Painful cramps, hypotension, repeated symptoms, and treatment-related accidents are common warning findings—not an acceptable goal.
Why answers are correct
- Healthy kidneys work 24 hours a day, seven days a week. Dialysis dose, frequency, duration, residual kidney function, and modality determine how closely treatment approximates that continuous work.
- “Dialysis patient” does not mean “unable to work or live normally.” The chapter emphasizes energy, appetite, sleep, intimacy, blood pressure, target labs, and healthy heart/bones as reasonable goals.
Limitations / traps
- Do not equate a completed treatment with full kidney replacement. Missed or shortened treatments reduce delivered clearance and increase fluid/waste exposure.
- Do not normalize cramps, hypotension, or feeling ill after every treatment; assess, protect, and report.
Clinical pearl / safety
- During or after treatment, observe symptoms and vital signs, check the system/access according to policy, notify the nurse promptly, and document accurately.
Exam cue
- Dialysis removes selected substances across a membrane; it does not replace every renal endocrine and regulatory function.
Compare / contrast: healthy kidneys and dialysis
| Kidney function | Healthy kidneys | Dialysis contribution |
|---|---|---|
| Water | Removes excess continuously | Removes some water during prescribed treatment |
| Waste | Removes waste continuously | Removes some waste on/through treatment periods |
| Electrolyte/acid–base | Fine, continuous control | Helps restore balance; changes are treatment- and prescription-dependent |
| Blood pressure/volume | Continuous water, sodium, and hormonal regulation | Helps by removing water and managing sodium, but may cause rapid shifts |
| EPO | Produces EPO signal for red-cell production | Does not restore EPO production; anemia therapy may be prescribed |
| Active vitamin D | Activates vitamin D | Does not activate it; active vitamin D may be given separately |
| Calcium/phosphorus | Controls balance continuously | Can adjust calcium in dialysate and remove some phosphorus, less completely |
Helping a patient choose
Study guide
- The seven dialysis approaches listed are:
- hand PD at home or work (CAPD);
- cycler PD at night (CCPD/APD);
- standard in-center HD;
- nocturnal in-center HD;
- standard home HD;
- daily home HD;
- nocturnal home HD.
- Ask what the patient values: keeping a job or school, caregiving, travel, eating and drinking flexibility, avoiding needles, sleeping, treatment privacy, proximity to a clinic, and available partner/space.
- Home options require training and a safe setup; they are not automatically easy. In-center options provide staff and supplies but impose clinic schedules and travel.
- The chapter points to the free My Kidney Life Plan decision aid from the Medical Education Institute and to home-dialysis education resources.
Why answers are correct
- The same modality can be helpful for one patient and burdensome for another. A person who gains fluid, travels far, works nights, or cares for children may benefit from a different schedule or home option.
Limitations / traps
- Never scare patients away from home therapy, imply that home is always superior, or use the absence of visible home patients as proof it fails.
- Do not place the whole home-treatment burden on a care partner when the patient can safely learn and perform tasks.
Clinical pearl / safety
- Encourage patients to learn more, involve the training nurse/doctor and social worker, and use teachable moments. Confirm that both patient and training nurse believe the plan is safe before going home.
Exam cue
- Explain all feasible options neutrally; refer individualized selection, eligibility, and prescription questions to the licensed team.
Peritoneal dialysis (PD)
Study guide
- PD is a daily self-care treatment that can occur at home or work. A catheter is placed in the abdomen; the patient’s peritoneum, rich in capillaries, serves as the exchange membrane.
- Sterile dialysate enters the abdomen, dwells for hours while wastes and water move into it, then drains and is replaced. One drain-and-fill cycle is an exchange.
- PD advantages include flexibility, portability, fewer diet/fluid limits than standard in-center HD, no treatment needles, and a sense of independence.
- The major infection concern is peritonitis, an infection of the peritoneum. Hand hygiene, masking, airflow control, and aseptic technique are essential. Catheter infection can also occur.
- Patients need room to store enough bags—potentially a several-week supply—and must maintain regular adequacy and residual-kidney-function testing.
- Residual kidney function can continue removing water and wastes. As it declines, the peritoneum may become less effective and a patient may need to change to HD.
CAPD — continuous ambulatory PD
- CAPD uses hand exchanges, commonly about four each day, often around meals and bedtime. A patient may shift timing slightly to fit life but must complete all prescribed exchanges.
- Each exchange takes roughly 20–30 minutes. A patient washes hands, controls room airflow, wears a mask until connections are complete, and follows the trained sterile process.
- The abdomen remains filled with dialysate between exchanges, so treatment is continuous. The patient must leave the room during the exchange to protect the sterile field.
CCPD/APD — cycler PD
- A machine performs exchanges overnight while the patient sleeps, commonly for about 8–10 hours. Long tubing may permit movement after connection, including a bathroom trip.
- Some patients add one or two daytime hand exchanges. The main advantage is keeping daytime hours available for work, school, or other activities.
Why answers are correct
- PD uses the patient’s own peritoneal capillaries rather than an external dialyzer. Its daily/continuous pattern can reduce large intermittent shifts, but it requires meticulous infection prevention and reliable self-care.
- CAPD and APD differ primarily in who/what performs the exchanges and when, not in the basic peritoneal membrane principle.
Limitations / traps
- “No needles” does not mean “no infection risk.” Breaks in aseptic technique can cause peritonitis.
- PD is not permanently effective for every patient; loss of residual function or declining membrane performance may require HD.
- A catheter, supplies, storage space, training, and a workable home environment are necessary; assess barriers rather than assuming refusal.
Clinical pearl / safety
- New abdominal symptoms, fever, cloudy or unusual effluent, drainage problems, or catheter-site changes during PD require prompt nurse notification and follow-up under the PD protocol.
Exam cue
- PD: catheter → sterile dialysate in → dwell → waste/water diffuse into fluid → drain → fresh exchange.
Compare / contrast: CAPD and CCPD/APD
| Feature | CAPD | CCPD/APD |
|---|---|---|
| Exchange method | Patient performs by hand | Cycler performs programmed exchanges |
| Usual timing | Several daytime/bedtime exchanges | Mainly overnight during sleep |
| Time pattern | Each exchange about 20–30 minutes | Roughly 8–10 hours connected overnight |
| Daytime impact | Must schedule multiple exchanges | Day usually freer; some need daytime exchange |
| Shared essentials | Peritoneal catheter, sterile dialysate, aseptic technique, monitoring |
Hemodialysis (HD) basics and vascular access
Study guide
- HD pumps blood out of the body through a dialyzer containing thousands of hollow fibers, then returns it. Blood flows inside the fibers; dialysate bathes the outside, and water/some wastes cross the fiber membrane.
- Only about half a cup of blood is outside the body at one time in the chapter’s example.
- Access types:
- Arteriovenous fistula (AVF): the patient’s artery and vein are surgically joined; preferred when vessels support it.
- Arteriovenous graft (AVG): a synthetic tube links artery and vein; often next choice when a fistula is not possible.
- Central venous catheter (CVC): a tube enters a large vein in the neck, chest, or groin with the tip near the vena cava; useful for urgent dialysis or poor vessels but more prone to infection and poor flow.
- Fistulas/grafts usually use two needles and bloodlines. A catheter can connect bloodlines without needles; a single-needle setup may be used in selected small or maturing accesses and some home-HD plans.
Why answers are correct
- Blood must travel through a safe, high-flow route to the dialyzer and back. The access determines infection, bleeding, flow, and longevity risks.
- A CVC is convenient for immediate access but is not automatically the best long-term access.
Limitations / traps
- Never cannulate, clamp, dress, or manipulate access outside training and facility policy. Protect the access from pressure, infection, and accidental disconnection.
- “The machine is running” does not prove adequate treatment; poor flow, alarms, access problems, and shortened time can reduce delivery.
Clinical pearl / safety
- Report bleeding, swelling, redness, drainage, pain, fever, absent/changed thrill or bruit, access alarms, or a sudden flow problem immediately.
Exam cue
- Fistula first when feasible; graft next; catheter often fastest but carries greater infection/flow risk.
Standard in-center HD (ICHD)
Study guide
- Standard ICHD commonly occurs in a clinic three times weekly, often Monday/Wednesday/Friday or Tuesday/Thursday/Saturday, for about 3–4 hours per treatment (roughly 9–12 hours weekly).
- The chapter contrasts this with healthy kidneys working 168 hours per week. Longer treatments generally remove fluid more gently and provide more clearance.
- A cited multinational study found at least four-hour treatments had lower mortality than shorter treatments, and each additional 30 minutes beyond four hours was associated with further risk reduction. These are associations, not permission to alter a prescription.
- Benefits: nurses/technicians are present, supplies are provided, no home partner is required, and the clinic can provide social contact.
- Limitations: fixed shifts, travel three times weekly, possible work/school and childcare conflict, greater diet/fluid and medication burden, and a two-day weekend gap.
- The “killer gap” is the two-day no-treatment interval for a three-times-weekly schedule. Patients may arrive after the weekend with the greatest weight gain and electrolyte imbalance; the chapter reports higher risk on Monday/Tuesday than other days.
- When medically prescribed, all three weekly treatments may be used to catch up while keeping ultrafiltration from exceeding a safe rate. Every-other-day treatment avoids the two-day gap but is uncommon in clinics.
- Incremental HD: patients with substantial urine output may begin with fewer/shorter treatments or slower flows, then increase as kidney function declines.
Why answers are correct
- Frequency and duration shape fluid removal, toxin control, symptoms, and cardiovascular stress. A patient’s “usual” cramps or hypotension still deserves assessment.
Limitations / traps
- Do not shorten treatment because the patient feels better or wants to leave without the nurse’s assessment and prescribed plan.
- Do not interpret the killer-gap discussion as a reason to change schedule independently.
Clinical pearl / safety
- A patient who arrives after a long gap with high weight gain, shortness of breath, weakness, chest symptoms, or confusion needs prompt assessment before and during treatment.
Exam cue
- Standard ICHD = usually 3 days/week; the long gap, not merely the single session, is a key risk.
Nocturnal in-center HD
Study guide
- Nocturnal ICHD occurs at night, commonly three nights weekly, with about 7–8 hours in the clinic while the patient sleeps.
- Compared with standard ICHD, it provides more treatment time, slower/gentler fluid removal, fewer cramps, fewer diet/fluid limits, and potentially fewer medicines. It can leave days open for work.
- The chapter cites improved heart findings, lower PTH/phosphorus, and better survival associations than standard ICHD. Availability is limited; patients may need to travel farther or prefer home therapy.
Why answers are correct
- More time allows the same general work to occur with less rapid fluid and solute change. Longer treatment is not simply “more of the same” when it changes hemodynamic stress.
Limitations / traps
- Do not assume nighttime treatment is available at every clinic or suitable for every patient. It still requires reliable attendance and access safety.
Clinical pearl / safety
- Explain that “night treatment” is a schedule and dose choice, not a reason to ignore alarms, access checks, or patient symptoms.
Standard home HD (SHHD)
Study guide
- Standard home HD may follow three-times-weekly or every-other-day schedules. Patient and/or care partner commonly train with a nurse for about 4–6 weeks.
- Training includes needle placement, supply ordering, machine operation, infection prevention, prescribed medicines, vital signs and samples, problem reporting, emergency response, and waste disposal.
- Home HD can offer flexible timing, longer or more frequent treatment, fewer symptoms and diet/fluid limits, and improved work/school compatibility.
- Requirements may include a trained partner, storage space, plumbing or electrical changes, and a safe home setup. Not every patient can or wants to meet them.
Why answers are correct
- The patient/care partner becomes responsible for day-to-day operations, but the home program remains a clinical relationship with training and support. Independence is not abandonment.
Limitations / traps
- Never assume a care partner must carry the whole treatment. The patient should learn as much as safely possible.
- Home treatment still has access, bleeding, infection, machine, and emergency risks; training and 24/7 support plans matter.
Clinical pearl / safety
- Confirm emergency procedures, supply availability, machine alarms, and who to call before encouraging home treatment. Escalate any home-treatment concern to the home program.
Daily home HD (DHHD)
Study guide
- DHHD commonly uses shorter treatments, about 2.5–4 hours, on 5–6 days each week, often at home because daily clinic travel is impractical.
- Shorter, frequent treatments can fit morning or evening routines, work, and family life. The chapter reports improvements such as better sleep and fewer restless-leg episodes in a cited experience.
- A smaller, easier-to-set-up machine can make short home treatments more practical. In 2017, the FDA approved solo daytime use of a NxStage machine; eligibility and current device rules still require the program’s assessment.
Why answers are correct
- More frequent treatment reduces the long interdialytic gap and may smooth fluid/solute shifts, but it increases the number of treatment days and self-care tasks.
Limitations / traps
- “Daily” does not mean treatment is automatically safer or suitable without training, access assessment, and a prescribed schedule.
Nocturnal home HD (NHHD)
Study guide
- NHHD is performed at home during sleep, commonly 3–7 nights weekly for 7–8 hours. A patient and care partner learn the setup; some programs monitor the treatment online.
- Needles and blood tubing are secured. Slow flow and blood-leak alarms provide time to respond, but the patient still needs training and an emergency plan.
- Studies cited in the chapter associate NHHD with higher albumin, less need for phosphate binders, better nutrition, fewer diet/fluid limits, better quality of life, and improved heart findings compared with standard ICHD.
- People far from a clinic or needing daytime hours for work or childcare may find NHHD attractive. Availability and suitability vary.
Why answers are correct
- Long, frequent overnight treatment approximates more continuous clearance and allows gentler fluid removal; benefits are population findings, not a guarantee.
Limitations / traps
- Sleeping through treatment does not eliminate access-disconnection or machine risks. Never bypass alarms or change settings without the home program.
Clinical pearl / safety
- Ensure the patient and partner can recognize blood-leak, access, and machine alarms and know when to stop/seek help according to the home program’s emergency plan.
Compare / contrast: HD options
| Option | Usual pattern | Main strengths | Main constraints |
|---|---|---|---|
| Standard ICHD | Clinic, ~3 times/week, ~3–4 hours | Staff/supplies present; no home partner | Fixed shifts, travel, long gap, more rapid shifts |
| Nocturnal ICHD | Clinic at night, ~3 nights/week, ~7–8 hours | Longer/gentler treatment; days free | Limited clinics, nighttime travel/availability |
| Standard home HD | Home, often 3 times/week or every other day | Flexible schedule; longer/more frequent options | Training, equipment, space, partner/support |
| Daily home HD | Home, ~5–6 days/week, ~2.5–4 hours | Frequent, shorter sessions; fewer long gaps | Many treatment days and self-care tasks |
| Nocturnal home HD | Home during sleep, ~3–7 nights/week, ~7–8 hours | Long gentle treatments; daytime free | Overnight safety, partner/program support, equipment |
Active medical management without dialysis
Study guide
- Without dialysis or transplant, kidney failure eventually causes death. Active medical management (also called conservative or comfort-focused management in this context) treats symptoms and supports quality of life without dialysis.
- It may fit some frail older adults, people with serious comorbid illness, or people with substantial pain for whom dialysis may not extend life or may impose more burden than benefit.
- Some patients may try dialysis and stop if symptoms and quality of life remain poor. The choice should be deliberate and supported, not the result of untreated depression, misinformation, or abandonment.
- Most major religions distinguish allowing natural death from suicide; beliefs and patient values should be respected.
- When treatment is stopped, the care team manages symptoms. Counseling, medication, a modality change, palliative care, and hospice may help patients and families.
- Advance directives let patients state desired care during a future health crisis and identify whether the clinic will honor those wishes. Patients may change clinics if needed to have wishes respected.
Why answers are correct
- “No dialysis” is not “no care.” It is an active plan centered on symptoms, goals, communication, and support.
- The decision belongs to the informed patient with the clinical team; technicians should not pressure, debate, or frame it as giving up.
Limitations / traps
- Never advise a patient to stop dialysis, predict an individual survival time, or treat a treatment decision as proof of depression or lack of hope.
- A comfort-focused plan still requires escalation of distressing symptoms and respect for advance directives.
Clinical pearl / safety
- If a patient expresses a wish to stop treatment, hopelessness, uncontrolled symptoms, or concern about goals of care, listen without judgment and promptly notify the nurse/social worker/appropriate team member.
Exam cue
- Conservative care is a planned, active treatment pathway focused on comfort and goals—not abandonment and not a technician decision.
Conclusion: what to carry forward
Study guide
- Kidney failure treatment affects every part of daily life. Patients who learn the options can choose, reconsider, or combine clinical advice with personal priorities.
- A technician’s role is to support informed choice, notice barriers and symptoms, communicate accurately, protect safety, and connect the patient with the licensed team.
Why answers are correct
- The best answer in a vignette often identifies both the physiologic issue and the patient-centered response: explain within scope, avoid bias, involve the nurse/doctor/social worker, and follow the prescribed plan.
Vocabulary
Uncommon words from this chapter. Plain definitions + a short dialysis-related example.
- autonomy
- The patient's right to make informed choices about their own care.
- Example. Staff should explain options without steering, so autonomy stays with the patient.
- immunosuppression
- Medicine that lowers immune attack so a transplanted kidney is not rejected.
- Example. Recipients need lifelong immunosuppression while the graft works.
- graft
- The donated kidney (or the synthetic tube used as access in later chapters).
- Example. A transplant graft may last years, but it is not a guaranteed cure.
- rejection
- The immune system attacking a transplanted organ as foreign.
- Example. New illness after transplant can be rejection and belongs to the transplant team.
- comorbidity
- Another illness that exists along with kidney failure.
- Example. Comorbidity can affect whether a person qualifies for transplant or home therapy.
- preemptive
- Done before dialysis is needed.
- Example. A preemptive transplant may be considered when GFR is about 20 or lower.
- desensitization
- Special immune treatment that can allow some mismatched transplants.
- Example. ABO-incompatible transplant may be possible after desensitization.
- residual
- What kidney work is still left.
- Example. As residual kidney function falls, PD may become less effective.
- aseptic
- Done in a way that keeps germs out of a sterile connection or space.
- Example. Breaks in aseptic technique can cause peritonitis.
- peritonitis
- Infection of the peritoneal lining of the belly.
- Example. Cloudy effluent or new abdominal pain on PD can mean peritonitis.
- dwell
- The time dialysate stays in the belly so wastes and water can move into it.
- Example. A PD exchange is drain, then fill, then a prescribed dwell.
- nocturnal
- Happening at night, often while the person sleeps.
- Example. Nocturnal HD gives more treatment time with slower fluid removal.
- incremental
- Started at a smaller dose and increased as needed.
- Example. Incremental HD may begin with fewer treatments while urine output is still high.
- interdialytic
- The time between dialysis treatments.
- Example. The two-day interdialytic gap can bring the greatest weight gain and electrolyte risk.
- hemodynamic
- Related to blood flow, blood pressure, and how the heart handles volume.
- Example. Longer HD can reduce hemodynamic stress from rapid fluid shifts.
- palliative
- Care focused on comfort and quality of life rather than curing the disease.
- Example. Palliative support can continue when a person chooses medical management without dialysis.
- advance directive
- Written wishes about future care if the person cannot speak for themselves.
- Example. An advance directive can say whether the clinic should start or continue dialysis in a crisis.
- fistula
- A surgical join of the patient's own artery and vein used for HD access.
- Example. A fistula is preferred when vessels can support it because it lasts longer and infects less often than a catheter.
- conservative care
- Active medical management of symptoms without dialysis or transplant.
- Example. Conservative care is planned comfort-focused treatment, not abandonment.
- semipermeable
- A barrier that lets some particles and water through but not others.
- Example. Dialysis works across a semipermeable membrane that separates blood from dialysate.
Must-know
- Name the major treatment pathways in the chapter: transplant, PD, HD variants, and active medical management without dialysis.
- Explain why transplant is not a cure and why immunosuppression continues after surgery.
- List the three donor sources and explain living donation, paired exchange, and chain donation.
- Distinguish KP/SPK transplant from kidney-only transplant and define preemptive transplant.
- State what KDPI and EPTS broadly estimate; recognize ABO-incompatible transplant as requiring desensitization.
- Compare continuous kidney function with dialysis’s partial, scheduled replacement of water and wastes.
- List the seven dialysis approaches in the module.
- Describe PD: catheter, peritoneal membrane, dialysate, dwell, drain, and exchange.
- Compare CAPD (hand exchanges) with CCPD/APD (cycler, usually overnight).
- Identify peritonitis and catheter infection as major PD safety concerns; explain why aseptic technique matters.
- Explain how residual kidney function affects PD effectiveness and modality changes.
- Describe HD blood flow through access → dialyzer fibers → return to patient, with dialysate outside the fibers.
- Compare AV fistula, AV graft, and CVC; know why fistula is preferred when feasible and CVC has greater infection/flow risk.
- State the usual standard ICHD pattern and explain the two-day “killer gap.”
- Explain incremental HD and why treatment time/frequency should never be changed independently.
- Compare standard and nocturnal in-center HD: schedule, treatment time, fluid removal, and availability.
- List home-HD training topics and home requirements, including partner/support, space, supplies, alarms, infection prevention, and emergency response.
- Compare standard home HD, daily home HD, and nocturnal home HD by timing, frequency, and patient-life fit.
- Why can longer or more frequent HD reduce rapid fluid/solute shifts? What risks remain?
- Define active medical management without dialysis and explain why it remains active care.
- Explain the technician response to a patient asking about modality change: provide unbiased scope-appropriate information and refer to the nurse/home-training team or doctor.
- In any treatment-option vignette: identify the patient goal, the physiologic/safety issue, the feasible options, the scope boundary, and the correct escalation/documentation step.